Abstract Triple-negative breast cancer (TNBC) is associated with a high rate of early recurrence and distant metastasis, frequent development of therapeutic resistance, and a poor prognosis.There is a lack of targeted therapies for this aggressive subtype of breast cancer.Identifying novel effective treatment modalities for TNBC remains an urgent a
This article addresses the synthesis of humour and paranoia in portrayals of artificial intelligence (AI) Gift Card in the popular American podcast Welcome to Night Vale (2012-).It argues that contrary to the Relief Theory, fusing humour and cyber-paranoia does not help release the tension (anxious energy) generated within the narrative.Rather, the
This paper illustrates how an emulator (or meta-model) of a tsunami code can be a useful tool to evaluate or qualify tsunami hazard levels associated with both specific and unknown tsunamigenic seismic sources.The meta-models are statistical tools permitting to drastically reduce the computational time necessary for tsunami simulations.As a consequ
BACKGROUND:Although epidemiological studies reveal that cigarette smoke (CS) facilitates the development and exacerbation of allergic asthma, these studies offer limited information on the mechanisms involved.The transmembrane glycoprotein CD44 is involved in cell adhesion and acts as a receptor for hyaluronic acid and osteopontin.We aimed to inves